| Product Name | Cofilin |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CFL1 antibody; CFL antibody; Cofilin-1 antibody; 18 kDa phosphoprotein antibody; p18 antibody; Cofilin antibody; non-muscle isoform antibody; |
| Product description | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus., |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cofilin. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CFL1 antibody CFL antibody Cofilin-1 antibody 18 kDa phosphoprotein antibody p18 antibody Cofilin antibody non-muscle isoform antibody |
|---|---|
| Molecular Weight(MW) | 19 kDa |
| SwissProt ID | P23528 |
|---|
| Positive Control | B-cell lymphoma,Brain,Cajal-Retzius cell,Epithelium,Fetal brain cortex,Lung,Ovary,Placenta,Platelet |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
