| Product Name | COX10 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | COX10 antibody; Protoheme IX farnesyltransferase antibody; mitochondrial antibody; Heme O synthase antibody; |
| Product description | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lys |
| Immunogen | The antiserum was produced against synthesized peptide derived from human COX10. AA range:98-147 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | COX10 antibody Protoheme IX farnesyltransferase antibody mitochondrial antibody Heme O synthase antibody |
|---|---|
| Molecular Weight(MW) | 49 kDa |
| SwissProt ID | Q12887 |
|---|
| Positive Control | Brain, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
