| Product Name | CRF |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CRH antibody; Corticoliberin antibody; Corticotropin-releasing factor antibody; CRF antibody; Corticotropin-releasing hormone antibody; |
| Product description | This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer's disease. Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation a |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CRF. AA range:104-153 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CRH antibody Corticoliberin antibody Corticotropin-releasing factor antibody CRF antibody Corticotropin-releasing hormone antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | P06850 |
|---|
| Positive Control | Brain, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
