| Product Name | CRMP-3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DPYSL4 antibody; CRMP3 antibody; ULIP4 antibody; Dihydropyrimidinase-related protein 4 antibody; DRP-4 antibody; Collapsin response mediator protein 3 antibody; CRMP-3 antibody; UNC33-like phosphoprotein 4 antibody; ULIP-4 antibody; |
| Product description | disease:Antibodies against post-translationally modified DPYSL4, also called anti-CV2 autoantibodies, are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct result of the tumor mass or metastasis, but attributed to remote effects of the cancer. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily. subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DPYSL4. AA range:91-140 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | DPYSL4 antibody CRMP3 antibody ULIP4 antibody Dihydropyrimidinase-related protein 4 antibody DRP-4 antibody Collapsin response mediator protein 3 antibody CRMP-3 antibody UNC33-like phosphoprotein 4 antibody ULIP-4 antibody |
|---|---|
| Molecular Weight(MW) | 62 kDa |
| SwissProt ID | O14531 |
|---|
| Positive Control | Brain,Fetal brain,Retina, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
