| Product Name | CRSP130 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MED23 antibody; ARC130 antibody; CRSP3 antibody; DRIP130 antibody; KIAA1216 antibody; SUR2 antibody; Mediator of RNA polymerase II transcription subunit 23 antibody; Activator-recruited cofactor 130 kDa component antibody; ARC130 antibody; Cofactor required for Sp1 transcriptional activation subunit 3 antibody; CRSP complex subu antibody; |
| Product description | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e. g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MED23. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | MED23 antibody ARC130 antibody CRSP3 antibody DRIP130 antibody KIAA1216 antibody SUR2 antibody Mediator of RNA polymerase II transcription subunit 23 antibody Activator-recruited cofactor 130 kDa component antibody ARC130 antibody Cofactor required for Sp1 transcriptional activation subunit 3 antibody CRSP complex subu antibody |
|---|---|
| Molecular Weight(MW) | 150 kDa |
| SwissProt ID | Q9ULK4 |
|---|
| Positive Control | Brain,Cervix carcinoma,Placenta,Prostate,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
