| Product Name | Cyclin A |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CCNA1 antibody; Cyclin-A1 antibody; CCNA2 antibody; CCN1 antibody; CCNA antibody; Cyclin-A2 antibody; Cyclin-A antibody; |
| Product description | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multi |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cyclin A. AA range:221-270 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRatMonkey |
| Concentration | 1mg/ml |
| Alternative Names | CCNA1 antibody Cyclin-A1 antibody CCNA2 antibody CCN1 antibody CCNA antibody Cyclin-A2 antibody Cyclin-A antibody |
|---|---|
| Molecular Weight(MW) | 53 kDa |
| Positive Control | Brain,Myeloid,Placenta,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
