| Product Name |
CYP11B1/2 |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
CYP11B1 antibody; S11BH antibody; Cytochrome P450 11B1 antibody; mitochondrial antibody; CYPXIB1 antibody; Cytochrome P-450c11 antibody; Cytochrome P450C11 antibody; Steroid 11-beta-hydroxylase antibody; CYP11B2 antibody; Cytochrome P450 11B2, mitochondrial antibody; Aldosterone synthase antibody; ALDOS antibody; Aldosterone-synthesizing enzyme antibody; antibody; |
| Product description |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. |
| Immunogen |
Synthesized peptide derived from the C-terminal region of human CYP11B1/2. |