| Product Name | CYP1A1/2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP1A1 antibody; Cytochrome P450 1A1 antibody; CYPIA1 antibody; Cytochrome P450 form 6 antibody; Cytochrome P450-C antibody; Cytochrome P450-P1 antibody; CYP1A2 antibody; Cytochrome P450 1A2 antibody; CYPIA2 antibody; Cytochrome P(3)450 antibody; Cytochrome P450 4 antibody; Cytochrome P450-P3 antibody; |
| Product description | This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cytochrome P450 1A1/2. AA range:71-120 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRatMonkey |
| Concentration | 1mg/ml |
| Alternative Names | CYP1A1 antibody Cytochrome P450 1A1 antibody CYPIA1 antibody Cytochrome P450 form 6 antibody Cytochrome P450-C antibody Cytochrome P450-P1 antibody CYP1A2 antibody Cytochrome P450 1A2 antibody CYPIA2 antibody Cytochrome P(3)450 antibody Cytochrome P450 4 antibody Cytochrome P450-P3 antibody |
|---|---|
| Molecular Weight(MW) | 58 kDa |
| Positive Control | Brain,Cervix,Epithelium,Placenta,Trachea, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
