| Product Name | CYP21A2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP21A2 antibody; CYP21 antibody; CYP21B antibody; Steroid 21-hydroxylase antibody; 21-OHase antibody; Cytochrome P-450c21 antibody; Cytochrome P450 21 antibody; Cytochrome P450 XXI antibody; Cytochrome P450-C21 antibody; Cytochrome P450-C21B antibody; |
| Product description | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cytochrome P450 21A2. AA range:151-200 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CYP21A2 antibody CYP21 antibody CYP21B antibody Steroid 21-hydroxylase antibody 21-OHase antibody Cytochrome P-450c21 antibody Cytochrome P450 21 antibody Cytochrome P450 XXI antibody Cytochrome P450-C21 antibody Cytochrome P450-C21B antibody |
|---|---|
| Molecular Weight(MW) | 55 kDa |
| SwissProt ID | P08686 |
|---|
| Positive Control | Adrenal gland,PCR rescued clones,Peripheral blood, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
