| Product Name | CYP24A1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP24A1 antibody; CYP24 antibody; 1 antibody; 25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial antibody; 24-OHase antibody; Vitamin D(3) 24-hydroxylase antibody; Cytochrome P450 24A1 antibody; Cytochrome P450-CC24 antibody; |
| Product description | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cytochrome P450 24A1. AA range:411-460 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CYP24A1 antibody CYP24 antibody 1 antibody 25-dihydroxyvitamin D(3) 24-hydroxylase mitochondrial antibody 24-OHase antibody Vitamin D(3) 24-hydroxylase antibody Cytochrome P450 24A1 antibody Cytochrome P450-CC24 antibody |
|---|---|
| Molecular Weight(MW) | 58 kDa |
| Cellular Localization | Mitochondrion. |
| SwissProt ID | Q07973 |
|---|
| Positive Control | PCR rescued clones, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
