| Product Name | CYP2A6 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP2A6 antibody; CYP2A3 antibody; Cytochrome P450 2A6 antibody; 1 antibody; 4-cineole 2-exo-monooxygenase antibody; CYPIIA6 antibody; Coumarin 7-hydroxylase antibody; Cytochrome P450 IIA3 antibody; Cytochrome P450(I) antibody; |
| Product description | This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2A6. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:500-1:2000 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CYP2A6 antibody CYP2A3 antibody Cytochrome P450 2A6 antibody 1 antibody 4-cineole 2-exo-monooxygenase antibody CYPIIA6 antibody Coumarin 7-hydroxylase antibody Cytochrome P450 IIA3 antibody Cytochrome P450(I) antibody |
|---|---|
| Molecular Weight(MW) | 56 kDa |
| SwissProt ID | P11509 |
|---|
| Positive Control | Hepatocyte,Liver,Mammary gland, |
|---|---|
| Application Notes | WB:1:500-1:2000 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
