| Product Name | CYP2C8 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP2C8 antibody; Cytochrome P450 2C8 antibody; CYPIIC8 antibody; Cytochrome P450 IIC2 antibody; Cytochrome P450 MP-12 antibody; Cytochrome P450 MP-20 antibody; Cytochrome P450 form 1 antibody; S-mephenytoin 4-hydroxylase antibody; |
| Product description | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CYP2C8. AA range:241-290 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIF |
| IHC:1:100-1:300 IF:1:50-200: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CYP2C8 antibody Cytochrome P450 2C8 antibody CYPIIC8 antibody Cytochrome P450 IIC2 antibody Cytochrome P450 MP-12 antibody Cytochrome P450 MP-20 antibody Cytochrome P450 form 1 antibody S-mephenytoin 4-hydroxylase antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | P10632 |
|---|
| Positive Control | Blood,Kidney,Liver, |
|---|---|
| Application Notes | IHC:1:100-1:300 IF:1:50-200: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
