| Product Name | CYP3A4/5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP3A4 antibody; CYP3A3 antibody; Cytochrome P450 3A4 antibody; 1 antibody; 8-cineole 2-exo-monooxygenase antibody; Albendazole monooxygenase antibody; Albendazole sulfoxidase antibody; CYPIIIA3 antibody; CYPIIIA4 antibody; Cytochrome P450 3A3 antibody; Cytochrome P450 HLp antibody; Cytochrome P450 NF-25 antibody; Cytochrome P450-PCN1 antibody; Nifedipine antibody; |
| Product description | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21. 1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isofor |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cytochrome P450 3A4/5. AA range:251-300 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CYP3A4 antibody CYP3A3 antibody Cytochrome P450 3A4 antibody 1 antibody 8-cineole 2-exo-monooxygenase antibody Albendazole monooxygenase antibody Albendazole sulfoxidase antibody CYPIIIA3 antibody CYPIIIA4 antibody Cytochrome P450 3A3 antibody Cytochrome P450 HLp antibody Cytochrome P450 NF-25 antibody Cytochrome P450-PCN1 antibody Nifedipine antibody |
|---|---|
| Molecular Weight(MW) | 57 kDa |
| Positive Control | Breast,Liver,PCR rescued clones, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
