| Product Name | CYP7B1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP7B1 antibody; 25-hydroxycholesterol 7-alpha-hydroxylase antibody; Cytochrome P450 7B1 antibody; Oxysterol 7-alpha-hydroxylase antibody; |
| Product description | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cytochrome P450 7B1. AA range:101-150 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CYP7B1 antibody 25-hydroxycholesterol 7-alpha-hydroxylase antibody Cytochrome P450 7B1 antibody Oxysterol 7-alpha-hydroxylase antibody |
|---|---|
| Molecular Weight(MW) | 58 kDa |
| SwissProt ID | O75881 |
|---|
| Positive Control | Colon,Hippocampus,Liver,Spleen, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
