| Product Name | Cystatin E/M |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CST6 antibody; Cystatin-M antibody; Cystatin-6 antibody; Cystatin-E antibody; |
| Product description | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype. |
| Immunogen | Synthesized peptide derived from the Internal region of human Cystatin E/M. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CST6 antibody Cystatin-M antibody Cystatin-6 antibody Cystatin-E antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q15828 |
|---|
| Positive Control | Blood,Prostate, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
