NBL1 antibody; DAN antibody; DAND1 antibody; Neuroblastoma suppressor of tumorigenicity 1 antibody; DAN domain family member 1 antibody; Protein N03 antibody; Zinc finger protein DAN antibody;
Product description
This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed.
Immunogen
The antiserum was produced against synthesized peptide derived from human NBL1. AA range:131-180
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHCIF
WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
NBL1 antibody DAN antibody DAND1 antibody Neuroblastoma suppressor of tumorigenicity 1 antibody DAN domain family member 1 antibody Protein N03 antibody Zinc finger protein DAN antibody