| Product Name | DAP-5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EIF4G2 antibody; DAP5 antibody; OK/SW-cl.75 antibody; Eukaryotic translation initiation factor 4 gamma 2 antibody; eIF-4-gamma 2 antibody; eIF-4G 2 antibody; eIF4G 2 antibody; Death-associated protein 5 antibody; DAP-5 antibody; p97 antibody; |
| Product description | Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human EIF4G2. AA range:41-90 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | EIF4G2 antibody DAP5 antibody OK/SW-cl.75 antibody Eukaryotic translation initiation factor 4 gamma 2 antibody eIF-4-gamma 2 antibody eIF-4G 2 antibody eIF4G 2 antibody Death-associated protein 5 antibody DAP-5 antibody p97 antibody |
|---|---|
| Molecular Weight(MW) | 90 kDa |
| SwissProt ID | P78344 |
|---|
| Positive Control | Brain,Colon adenocarcinoma,Epithelium,Kidney,Liver, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
