AKR1C3 antibody; DDH1 antibody; HSD17B5 antibody; KIAA0119 antibody; PGFS antibody; Aldo-keto reductase family 1 member C3 antibody; 17-beta-hydroxysteroid dehydrogenase type 5 antibody; 17-beta-HSD 5 antibody; 3-alpha-HSD type II antibody; brain antibody; 3-alpha-hydroxysteroid dehydrogenase type 2 antibody; 3-alpha-HSD type 2 antibody; Chlordec antibody;
Product description
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.
Immunogen
The antiserum was produced against synthesized peptide derived from human AKR1C3. AA range:191-240
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
AKR1C3 antibody DDH1 antibody HSD17B5 antibody KIAA0119 antibody PGFS antibody Aldo-keto reductase family 1 member C3 antibody 17-beta-hydroxysteroid dehydrogenase type 5 antibody 17-beta-HSD 5 antibody 3-alpha-HSD type II antibody brain antibody 3-alpha-hydroxysteroid dehydrogenase type 2 antibody 3-alpha-HSD type 2 antibody Chlordec antibody