| Product Name | Defensin α4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DEFA4 antibody; DEF4 antibody; Neutrophil defensin 4 antibody; Defensin antibody; alpha 4 antibody; HNP-4 antibody; HP-4 antibody; |
| Product description | Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Defensin alpha4. AA range:27-76 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DEFA4 antibody DEF4 antibody Neutrophil defensin 4 antibody Defensin antibody alpha 4 antibody HNP-4 antibody HP-4 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | P12838 |
|---|
| Positive Control | Bone marrow,Lung and heart,PCR rescued clones, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
