| Product Name | Dexras2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RASD2 antibody; TEM2 antibody; GTP-binding protein Rhes antibody; Ras homolog enriched in striatum antibody; Tumor endothelial marker 2 antibody; |
| Product description | This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RASD2. AA range:217-266 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | RASD2 antibody TEM2 antibody GTP-binding protein Rhes antibody Ras homolog enriched in striatum antibody Tumor endothelial marker 2 antibody |
|---|---|
| Molecular Weight(MW) | 35 kDa |
| SwissProt ID | Q96D21 |
|---|
| Positive Control | Endothelial cell,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
