| Product Name | DMGDH |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DMGDH antibody; Dimethylglycine dehydrogenase antibody; mitochondrial antibody; ME2GLYDH antibody; |
| Product description | This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DMGDH. AA range:817-866 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DMGDH antibody Dimethylglycine dehydrogenase antibody mitochondrial antibody ME2GLYDH antibody |
|---|---|
| Molecular Weight(MW) | 97 kDa |
| SwissProt ID | Q9UI17 |
|---|
| Positive Control | Kidney,Trachea, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
