| Product Name | DMPK |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DMPK antibody; DM1PK antibody; MDPK antibody; Myotonin-protein kinase antibody; MT-PK antibody; DM-kinase antibody; DMK antibody; DM1 protein kinase antibody; DMPK antibody; Myotonic dystrophy protein kinase antibody; |
| Product description | The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DMPK. AA range:11-60 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DMPK antibody DM1PK antibody MDPK antibody Myotonin-protein kinase antibody MT-PK antibody DM-kinase antibody DMK antibody DM1 protein kinase antibody DMPK antibody Myotonic dystrophy protein kinase antibody |
|---|---|
| Molecular Weight(MW) | 70 kDa |
| SwissProt ID | Q09013 |
|---|
| Positive Control | Brain,Heart,Muscle, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
