| Product Name | DOCK 2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DOCK2 antibody; KIAA0209 antibody; Dedicator of cytokinesis protein 2 antibody; |
| Product description | The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. |
| Immunogen | Synthesized peptide derived from the Internal region of human DOCK 2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | DOCK2 antibody KIAA0209 antibody Dedicator of cytokinesis protein 2 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q92608 |
|---|
| Positive Control | Blood,Bone marrow,Colon,Liver,Synovial membrane, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
