| Product Name | Dok-5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DOK5 antibody; C20orf180 antibody; Docking protein 5 antibody; Downstream of tyrosine kinase 5 antibody; Insulin receptor substrate 6 antibody; IRS-6 antibody; IRS6 antibody; |
| Product description | The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DOK5. AA range:101-150 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | DOK5 antibody C20orf180 antibody Docking protein 5 antibody Downstream of tyrosine kinase 5 antibody Insulin receptor substrate 6 antibody IRS-6 antibody IRS6 antibody |
|---|---|
| Molecular Weight(MW) | 36 kDa |
| SwissProt ID | Q9P104 |
|---|
| Positive Control | Brain,Kidney,Skeletal muscle, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
