| Product Name | DSCR 1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RCAN1 antibody; ADAPT78 antibody; CSP1 antibody; DSC1 antibody; DSCR1 antibody; Calcipressin-1 antibody; Adapt78 antibody; Down syndrome critical region protein 1 antibody; Myocyte-enriched calcineurin-interacting protein 1 antibody; MCIP1 antibody; Regulator of calcineurin 1 antibody; |
| Product description | The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RCAN1. AA range:201-250 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | RCAN1 antibody ADAPT78 antibody CSP1 antibody DSC1 antibody DSCR1 antibody Calcipressin-1 antibody Adapt78 antibody Down syndrome critical region protein 1 antibody Myocyte-enriched calcineurin-interacting protein 1 antibody MCIP1 antibody Regulator of calcineurin 1 antibody |
|---|---|
| Molecular Weight(MW) | 22 kDa |
| SwissProt ID | P53805 |
|---|
| Positive Control | Heart,Lung,Mammary gland,Tongue,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
