| Product Name | Dynactin 2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DCTN2 antibody; DCTN50 antibody; Dynactin subunit 2 antibody; 50 kDa dynein-associated polypeptide antibody; Dynactin complex 50 kDa subunit antibody; DCTN-50 antibody; p50 dynamitin antibody; |
| Product description | This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human p50 Dynamitin. AA range:341-390 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | DCTN2 antibody DCTN50 antibody Dynactin subunit 2 antibody 50 kDa dynein-associated polypeptide antibody Dynactin complex 50 kDa subunit antibody DCTN-50 antibody p50 dynamitin antibody |
|---|---|
| Molecular Weight(MW) | 50 kDa |
| SwissProt ID | Q13561 |
|---|
| Positive Control | Brain,Embryonic kidney,Fetal brain cortex,Placenta,Platelet,Skin,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
