| Product Name | Dyrk1A |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DYRK1A antibody; DYRK antibody; MNB antibody; MNBH antibody; Dual specificity tyrosine-phosphorylation-regulated kinase 1A antibody; Dual specificity YAK1-related kinase antibody; HP86 antibody; Protein kinase minibrain homolog antibody; MNBH antibody; hMNB antibody; |
| Product description | This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' co |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DYR1A. AA range:21-70 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | DYRK1A antibody DYRK antibody MNB antibody MNBH antibody Dual specificity tyrosine-phosphorylation-regulated kinase 1A antibody Dual specificity YAK1-related kinase antibody HP86 antibody Protein kinase minibrain homolog antibody MNBH antibody hMNB antibody |
|---|---|
| Molecular Weight(MW) | 90 kDa |
| SwissProt ID | Q13627 |
|---|
| Positive Control | Brain,Fetal brain,Platelet,Promyelocytic le |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
