| Product Name | E-cadherin |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDH1 antibody; CDHE antibody; UVO antibody; Cadherin-1 antibody; CAM 120/80 antibody; Epithelial cadherin antibody; E-cadherin antibody; Uvomorulin antibody; CD antigen CD324 antibody; CDH2 antibody; CDHN antibody; NCAD antibody; Cadherin-2 antibody; CDw325 antibody; Neural cadherin antibody; N-cadherin antibody; CD antigen CD325 antibody; CDH3 antibody; CDHP antibody; Cadherin-3 antibody; Placental cadherin antibody; P-cadhe antibody; |
| Product description | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cadherin. AA range:833-882 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CDH1 antibody CDHE antibody UVO antibody Cadherin-1 antibody CAM 120/80 antibody Epithelial cadherin antibody E-cadherin antibody Uvomorulin antibody CD antigen CD324 antibody CDH2 antibody CDHN antibody NCAD antibody Cadherin-2 antibody CDw325 antibody Neural cadherin antibody N-cadherin antibody CD antigen CD325 antibody CDH3 antibody CDHP antibody Cadherin-3 antibody Placental cadherin antibody P-cadhe antibody |
|---|---|
| Molecular Weight(MW) | 125-130 kDa |
| Positive Control | Brain,Epidermal carcinoma,Hippocampus,Liver,Pancreas,Placenta,Tongue, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
