| Product Name | eIF4G |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EIF4G1 antibody; EIF4F antibody; EIF4G antibody; EIF4GI antibody; Eukaryotic translation initiation factor 4 gamma 1 antibody; eIF-4-gamma 1 antibody; eIF-4G 1 antibody; eIF-4G1 antibody; p220 antibody; |
| Product description | The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human eIF4G. AA range:1074-1123 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIFWB |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | EIF4G1 antibody EIF4F antibody EIF4G antibody EIF4GI antibody Eukaryotic translation initiation factor 4 gamma 1 antibody eIF-4-gamma 1 antibody eIF-4G 1 antibody eIF-4G1 antibody p220 antibody |
|---|---|
| Molecular Weight(MW) | 175 kDa |
| SwissProt ID | Q04637 |
|---|
| Positive Control | Brain,Endometrial tumor,Epithelium,Pancreas,Placent |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
