| Product Name | ELL |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ELL antibody; C19orf17 antibody; RNA polymerase II elongation factor ELL antibody; Eleven-nineteen lysine-rich leukemia protein antibody; |
| Product description | disease:A chromosomal translocation involving ELL is found in acute leukemias. Translocation t(11;19)(q23;p13. 1) with MLL/HRX. The result is a rogue activator protein. Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Belongs to the ELL/occludin family. subcellular location:Colocalizes with EAF2 to nuclear speckles. Also localized to Cajal (coiled) bodies. subunit:Interacts with EAF1 and EAF2. tissue specificity:Expressed in all tissues tested. Highest levels found in placenta, skeletal muscle, testis and peripheral blood leukocytes. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ELL. AA range:91-140 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | ELL antibody C19orf17 antibody RNA polymerase II elongation factor ELL antibody Eleven-nineteen lysine-rich leukemia protein antibody |
|---|---|
| Molecular Weight(MW) | 65 kDa |
| SwissProt ID | P55199 |
|---|
| Positive Control | Brain,Epithelium,Fetal brain, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
