| Product Name | Endophilin I |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SH3GL2 antibody; CNSA2 antibody; SH3D2A antibody; Endophilin-A1 antibody; EEN-B1 antibody; Endophilin-1 antibody; SH3 domain protein 2A antibody; SH3 domain-containing GRB2-like protein 2 antibody; |
| Product description | domain:An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes. The BAR domain dimer forms a rigid crescent shaped bundle of helices with the pair of second amphipathic helices protruding towards the membrane-binding surface. Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. miscellaneous:HeLa cells expressing the N-BAR domain of SH3GL2 show tubulation of the plasma membrane. The N-BAR domain binds liposomes and induces formation of tubules from liposomes. The N-terminal amphipathic helix is required for liposome binding. The second amphipathic helix enhances liposome tubulation. Belongs to the endophilin family. Contains 1 BAR domain. Contains 1 SH3 domain. subcellular location:Concentrated in presynaptic nerve terminals in neurons. subunit:Monomer; in cytoplasm. Homodimer; when associated with membranes (By similarity). Interacts with SYNJ1 and DNM1. Interacts with MAP4K3; the interaction appears to regulate MAP4K3-mediated JNK activation. Interacts with PDCD6IP. tissue specificity:Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum. |
| Immunogen | Synthesized peptide derived from Endophilin I . at AA range: 30-110 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | SH3GL2 antibody CNSA2 antibody SH3D2A antibody Endophilin-A1 antibody EEN-B1 antibody Endophilin-1 antibody SH3 domain protein 2A antibody SH3 domain-containing GRB2-like protein 2 antibody |
|---|---|
| Molecular Weight(MW) | 39 kDa |
| SwissProt ID | Q99962 |
|---|
| Positive Control | Brain,Epithelium,Fetal brain,Human fetal brain, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
