| Product Name | ERI1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ERI1 antibody; 3'EXO antibody; THEX1 antibody; 3'-5' exoribonuclease 1 antibody; 3'-5' exonuclease ERI1 antibody; Eri-1 homolog antibody; Histone mRNA 3'-end-specific exoribonuclease antibody; Histone mRNA 3'-exonuclease 1 antibody; Protein 3'hExo antibody; HEXO antibody; |
| Product description | cofactor:Binds 2 magnesium ions per subunit. enzyme regulation:Although it can bind simultaneously with SLBP to the 3'-end of histone mRNA, the presence of SLBP prevents the exonuclease activity. RNA exonuclease that binds to the 3'-end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Required for 5. 8S rRNA 3'-end processing. sequence caution:Translated as Leu. Contains 1 exonuclease domain. Contains 1 SAP domain. subunit:Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs. Requires the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Binds to 40S and 60S ribosomal subunits and to 80S assembled ribosomes. Also binds to 5. 8s ribosomal RNA. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ERI1. AA range:261-310 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ERI1 antibody 3'EXO antibody THEX1 antibody 3'-5' exoribonuclease 1 antibody 3'-5' exonuclease ERI1 antibody Eri-1 homolog antibody Histone mRNA 3'-end-specific exoribonuclease antibody Histone mRNA 3'-exonuclease 1 antibody Protein 3'hExo antibody HEXO antibody |
|---|---|
| Molecular Weight(MW) | 37 kDa |
| SwissProt ID | Q8IV48 |
|---|
| Positive Control | Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
