| Product Name | EWS |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EWSR1 antibody; EWS antibody; RNA-binding protein EWS antibody; EWS oncogene antibody; Ewing sarcoma breakpoint region 1 protein antibody; |
| Product description | This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been id |
| Immunogen | The antiserum was produced against synthesized peptide derived from human EWSR1. AA range:403-452 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | EWSR1 antibody EWS antibody RNA-binding protein EWS antibody EWS oncogene antibody Ewing sarcoma breakpoint region 1 protein antibody |
|---|---|
| Molecular Weight(MW) | 68 kDa |
| SwissProt ID | Q01844 |
|---|
| Positive Control | Colon carcinoma,Fetal brain,Lymph,Muscle,Ovarian carcinoma,Placenta,Skin, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
