| Product Name |
Fes |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
FES antibody; FPS antibody; Tyrosine-protein kinase Fes/Fps antibody; Feline sarcoma/Fujinami avian sarcoma oncogene homolog antibody; Proto-oncogene c-Fes antibody; Proto-oncogene c-Fps antibody; p93c-fes antibody; |
| Product description |
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms., |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human FES. AA range:131-180 |