| Product Name | Fhit |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FHIT antibody; Bis(5'-adenosyl)-triphosphatase antibody; AP3A hydrolase antibody; AP3Aase antibody; Diadenosine 5' antibody; 5'''-P1,P3-triphosphate hydrolase antibody; Dinucleosidetriphosphatase antibody; Fragile histidine triad protein antibody; |
| Product description | This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FHIT. AA range:81-130 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | FHIT antibody Bis(5'-adenosyl)-triphosphatase antibody AP3A hydrolase antibody AP3Aase antibody Diadenosine 5' antibody 5'''-P1 P3-triphosphate hydrolase antibody Dinucleosidetriphosphatase antibody Fragile histidine triad protein antibody |
|---|---|
| Molecular Weight(MW) | 16 kDa |
| SwissProt ID | P49789 |
|---|
| Positive Control | Brain,Colon,Lower lip,Thyroid,Tongue,Tonsil,Uterine cervix, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
