| Product Name | FIR |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FARP2 antibody; KIAA0793 antibody; PLEKHC3 antibody; FERM antibody; RhoGEF and pleckstrin domain-containing protein 2 antibody; FERM domain including RhoGEF antibody; FIR antibody; Pleckstrin homology domain-containing family C member 3 antibody; PH domain-containing family C member 3 antibody; |
| Product description | Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Contains 1 DH (DBL-homology) domain. Contains 1 FERM domain. Contains 2 PH domains. subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FIR. AA range:331-380 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:500-1:2000 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | FARP2 antibody KIAA0793 antibody PLEKHC3 antibody FERM antibody RhoGEF and pleckstrin domain-containing protein 2 antibody FERM domain including RhoGEF antibody FIR antibody Pleckstrin homology domain-containing family C member 3 antibody PH domain-containing family C member 3 antibody |
|---|---|
| Molecular Weight(MW) | 119 kDa |
| SwissProt ID | O94887 |
|---|
| Positive Control | Brain,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
