| Product Name | Fnk |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PLK3 antibody; CNK antibody; FNK antibody; PRK antibody; Serine/threonine-protein kinase PLK3 antibody; Cytokine-inducible serine/threonine-protein kinase antibody; FGF-inducible kinase antibody; Polo-like kinase 3 antibody; PLK-3 antibody; Proliferation-related kinase antibody; |
| Product description | The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PLK3. AA range:231-280 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | PLK3 antibody CNK antibody FNK antibody PRK antibody Serine/threonine-protein kinase PLK3 antibody Cytokine-inducible serine/threonine-protein kinase antibody FGF-inducible kinase antibody Polo-like kinase 3 antibody PLK-3 antibody Proliferation-related kinase antibody |
|---|---|
| Molecular Weight(MW) | 70 kDa |
| SwissProt ID | Q9H4B4 |
|---|
| Positive Control | Aorta endothelial cell,Brain,Embryo,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
