| Product Name | FucT-III |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FUT3 antibody; FT3B antibody; LE antibody; Galactoside 3(4)-L-fucosyltransferase antibody; Blood group Lewis alpha-4-fucosyltransferase antibody; Lewis FT antibody; Fucosyltransferase 3 antibody; Fucosyltransferase III antibody; FucT-III antibody; |
| Product description | The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FUT3. AA range:91-140 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | FUT3 antibody FT3B antibody LE antibody Galactoside 3(4)-L-fucosyltransferase antibody Blood group Lewis alpha-4-fucosyltransferase antibody Lewis FT antibody Fucosyltransferase 3 antibody Fucosyltransferase III antibody FucT-III antibody |
|---|---|
| Molecular Weight(MW) | 42 kDa |
| SwissProt ID | P21217 |
|---|
| Positive Control | Blood,Colon,Liver,Lung,Rectum,Small intestine,Squamous cell carcino |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
