GAB2 antibody; KIAA0571 antibody; GRB2-associated-binding protein 2 antibody; GRB2-associated binder 2 antibody; Growth factor receptor bound protein 2-associated protein 2 antibody; pp100 antibody;
Product description
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
Immunogen
The antiserum was produced against synthesized peptide derived from human Gab2. AA range:125-174
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:500-1:2000 IHC:1:100-1:300
Species Reactivity
HumanMouseRatMonkey
Concentration
1mg/ml
Target Information
Alternative Names
GAB2 antibody KIAA0571 antibody GRB2-associated-binding protein 2 antibody GRB2-associated binder 2 antibody Growth factor receptor bound protein 2-associated protein 2 antibody pp100 antibody