| Product Name | GFRα-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GFRA1 antibody; GDNFRA antibody; RETL1 antibody; TRNR1 antibody; GDNF family receptor alpha-1 antibody; GDNF receptor alpha-1 antibody; GDNFR-alpha-1 antibody; GFR-alpha-1 antibody; RET ligand 1 antibody; TGF-beta-related neurotrophic factor receptor 1 antibody; |
| Product description | This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GFR alpha-1. AA range:51-100 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | GFRA1 antibody GDNFRA antibody RETL1 antibody TRNR1 antibody GDNF family receptor alpha-1 antibody GDNF receptor alpha-1 antibody GDNFR-alpha-1 antibody GFR-alpha-1 antibody RET ligand 1 antibody TGF-beta-related neurotrophic factor receptor 1 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | P56159 |
|---|
| Positive Control | Eye,Kidney,Substantia nigra,Thyroid carcinoma, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
