| Product Name | Girdin |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CCDC88A antibody; APE antibody; GRDN antibody; KIAA1212 antibody; Girdin antibody; Akt phosphorylation enhancer antibody; APE antibody; Coiled-coil domain-containing protein 88A antibody; G alpha-interacting vesicle-associated protein antibody; GIV antibody; Girders of actin filament antibody; Hook-related protein 1 antibody; HkRP1 antibody; |
| Product description | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Girdin. AA range:1383-1432 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | CCDC88A antibody APE antibody GRDN antibody KIAA1212 antibody Girdin antibody Akt phosphorylation enhancer antibody APE antibody Coiled-coil domain-containing protein 88A antibody G alpha-interacting vesicle-associated protein antibody GIV antibody Girders of actin filament antibody Hook-related protein 1 antibody HkRP1 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q3V6T2 |
|---|
| Positive Control | Amygdala,Bone marrow,Brain,Fetal brain,Hypothalamus,Testis,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
