| Product Name | GIT2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GIT2 antibody; KIAA0148 antibody; ARF GTPase-activating protein GIT2 antibody; ARF GAP GIT2 antibody; Cool-interacting tyrosine-phosphorylated protein 2 antibody; CAT-2 antibody; CAT2 antibody; G protein-coupled receptor kinase-interactor 2 antibody; GRK-interacting protein 2 antibody; |
| Product description | This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GIT2. AA range:361-410 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | GIT2 antibody KIAA0148 antibody ARF GTPase-activating protein GIT2 antibody ARF GAP GIT2 antibody Cool-interacting tyrosine-phosphorylated protein 2 antibody CAT-2 antibody CAT2 antibody G protein-coupled receptor kinase-interactor 2 antibody GRK-interacting protein 2 antibody |
|---|---|
| Molecular Weight(MW) | 84 kDa |
| SwissProt ID | Q14161 |
|---|
| Positive Control | B-cell,Bone marrow,Cerebellum,Dermoid cancer,Epithelium,Skin,T-cell, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
