| Product Name | GluR-δ2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GRID2 antibody; GLURD2 antibody; Glutamate receptor delta-2 subunit antibody; GluR delta-2 subunit antibody; |
| Product description | The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GRID2. AA range:831-880 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:500-1:2000 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | GRID2 antibody GLURD2 antibody Glutamate receptor delta-2 subunit antibody GluR delta-2 subunit antibody |
|---|---|
| Molecular Weight(MW) | 113 kDa |
| SwissProt ID | O43424 |
|---|
| Positive Control | Brain,Cerebellum,PCR rescued clones, |
|---|---|
| Application Notes | WB:1:500-1:2000 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
