WB
Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night.ICC/IF
Immunofluorescence analysis of A549 cells, using GNRHR Antibody. The picture on the right is blocked with the synthesized peptide.| Product Name | GnRH-R Rabbit pAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gen |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GNRHR. AA range:41-90 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFWB |
| WB:1:500-1:2000 ICC/IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | GNRHR antibody GRHR antibody Gonadotropin-releasing hormone receptor antibody GnRH receptor antibody GnRH-R antibody |
|---|---|
| Molecular Weight(MW) | 37 kDa |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| SwissProt ID | P30968 |
|---|
WB
Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night.
ICC/IF
Immunofluorescence analysis of A549 cells, using GNRHR Antibody. The picture on the right is blocked with the synthesized peptide.| Application Notes | WB:1:500-1:2000 ICC/IF:1:100-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
