| Product Name | Golgin 45 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BLZF1 antibody; JEM1 antibody; Golgin-45 antibody; Basic leucine zipper nuclear factor 1 antibody; JEM-1 antibody; p45 basic leucine-zipper nuclear factor antibody; |
| Product description | caution:Because of the presence of a potential basic motif and leucine-zipper domain, PubMed:9129147 and PubMed:11056056 have thought that BLZF1 is a potential transcription factor. They found it localized in the nucleus, except isoform 2, which was cytoplasmic. However, homology at several typical position for basic or hydrophobic residues is missing. Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface. induction:Up-regulated by retinoids. subunit:Interacts with GORASP2 and with the GTP-bound form of RAB2, but not with other Golgi Rab proteins. GORASP2 and BLZF1 form a RAB2 effector complex on medial Golgi. tissue specificity:Ubiquitous. Also found in cell lines derived from several hematopoietic pathologies, such as T-cell leukemia, pro-B, pre-B, myeloma, and plasmacytoma cell lines, but not in Burkitt lymphoma cells. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BLZF1. AA range:10-59 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | BLZF1 antibody JEM1 antibody Golgin-45 antibody Basic leucine zipper nuclear factor 1 antibody JEM-1 antibody p45 basic leucine-zipper nuclear factor antibody |
|---|---|
| Molecular Weight(MW) | 47 kDa |
| SwissProt ID | Q9H2G9 |
|---|
| Positive Control | Liver,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
