| Product Name | GRB10 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GRB10 antibody; GRBIR antibody; KIAA0207 antibody; Growth factor receptor-bound protein 10 antibody; GRB10 adapter protein antibody; Insulin receptor-binding protein Grb-IR antibody; |
| Product description | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GRB10. AA range:33-82 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GRB10 antibody GRBIR antibody KIAA0207 antibody Growth factor receptor-bound protein 10 antibody GRB10 adapter protein antibody Insulin receptor-binding protein Grb-IR antibody |
|---|---|
| Molecular Weight(MW) | 67 kDa |
| SwissProt ID | Q13322 |
|---|
| Positive Control | Bone marrow,Brain,Cerebellum,Epithelium,Kidney,Skeletal muscle,Test |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
