| Product Name | GRF-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARHGAP35 antibody; GRF1 antibody; GRLF1 antibody; KIAA1722 antibody; Rho GTPase-activating protein 35 antibody; Glucocorticoid receptor DNA-binding factor 1 antibody; Glucocorticoid receptor repression factor 1 antibody; GRF-1 antibody; Rho GAP p190A antibody; p190-A antibody; |
| Product description | The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GRF-1. AA range:1071-1120 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ARHGAP35 antibody GRF1 antibody GRLF1 antibody KIAA1722 antibody Rho GTPase-activating protein 35 antibody Glucocorticoid receptor DNA-binding factor 1 antibody Glucocorticoid receptor repression factor 1 antibody GRF-1 antibody Rho GAP p190A antibody p190-A antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q9NRY4 |
|---|
| Positive Control | Brain,Epithelium,Mammary cancer,Platelet, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
