| Product Name | GUF1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GUF1 antibody; Translation factor GUF1 antibody; mitochondrial antibody; Elongation factor 4 homolog antibody; EF-4 antibody; GTPase GUF1 antibody; Ribosomal back-translocase antibody; |
| Product description | This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GUF1 antibody Translation factor GUF1 antibody mitochondrial antibody Elongation factor 4 homolog antibody EF-4 antibody GTPase GUF1 antibody Ribosomal back-translocase antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q8N442 |
|---|
| Positive Control | Brain,Colon,Lung adenocarcinoma,Teratocarcinoma, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
