| Product Name | HLA-DPα1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HLA-DPA1 antibody; HLA-DP1A antibody; HLASB antibody; HLA class II histocompatibility antigen antibody; DP alpha 1 chain antibody; DP(W3) antibody; DP(W4) antibody; HLA-SB alpha chain antibody; MHC class II DP3-alpha antibody; MHC class II DPA1 antibody; |
| Product description | HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. |
| Immunogen | Synthesized peptide derived from the Internal region of human HLA-DPα1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | HLA-DPA1 antibody HLA-DP1A antibody HLASB antibody HLA class II histocompatibility antigen antibody DP alpha 1 chain antibody DP(W3) antibody DP(W4) antibody HLA-SB alpha chain antibody MHC class II DP3-alpha antibody MHC class II DPA1 antibody |
|---|---|
| Molecular Weight(MW) | 29 kDa |
| SwissProt ID | P20036 |
|---|
| Positive Control | Brain,Primary B-Cells,Thymus, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
