| Product description |
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis. sequence caution:Translation N-terminally extended. Belongs to the H2. 0 homeobox family. Contains 1 homeobox DNA-binding domain. tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain. |